Director: Ramakrishna V. Hosur

Ramkrishan Hosur

Basic Information:

Born, 1953; B. Sc from Karnatak University; M. Sc (Chemistry) from IIT-Bombay; Ph. D from TIFR (Mumbai university); Post-doc at ETH Zurich (Prof. Kurt Wuthrich, NL); Employed at TIFR since 1978, currently, Senior Professor.

Research:

Pioneered research in biomolecular NMR, molecular biophysics, biophysical chemistry. Published over 150 research articles in journals; Written and Edited books.; Taught  courses at TIFR, IIT-Bombay, IIT-Roorkee on NMR,  mathematics, biophysics; Guided 20 Ph. D students.

Key Contributions:

Discovered new structural motifs in quadruplex DNA structures: A-tetrad, T-tetrad, C-tetrad. • Developed new multidimensional NMR pulse sequences. • Elucidated the folding hierarchy in HIV-1 protease.  • Developed ‘scaling techniques’ for sensitivity and resolution enhancement. • Suggested a pH switch mechanism for cargo trafficking by DLC8 protein inside living cells. • Elucidated the native state energy landscape, and structural and dynamic characteristics of SUMO-1 protein along the equilibrium folding pathways;  demonstrated that the native contacts do not progress monotonously. • Elucidated by NMR the self-association pathway of GED domain of dynamin into a large >5 MDa assembly.

Recognitions:

Convener, National Facility for high field NMR; Member of sectional committees of INSA, Indian Academy of Sciences AND NATIONAL Academy of Sciences; DST, CSIR and DBT expert committees; Chair, IUPAB national committee of INSA (2008-2011); council member, INSA (2008-2010); RC member, IICB, Kolkata; President, Indian Biophysical Society; President, new biology section of Indian Science Congress, 2005; President, National Magnetic Resonance Society (NMRS) (2009-11); Council Member, Centre for Biomedical Research, Lucknow; Member, Council of International Conference on Magnetic Resonance in Biological Systems (2004-2014)

Academy Fellowships:

Indian Academy of Sciences (1994); National Academy of Sciences (1997); Indian National Science Academy (1995); The World Academy of Sciences (2008)

Awards:

  • Padma Shri 2014
  • JC Bose Fellowship (2007-2012)
  • Jagdish Shankar lecture (2003)
  • R. K. Asundi lecture (1998)
  • 3rd annual award of society for cancer research (1998)
  • B. M. Birla award (1992)
  • B. D. Tilak lecture (1989)
  • INSA young scientist (1984)
  • BRUKER young scientist (1983)

Address

UM-DAE Centre for Excellence in Basic Sciences
Health Centre, University of Mumbai,
Vidyanagari Campus, Kalina, Santacruz (East), Mumbai 400098, India.
Phone: 91-22-26524983
Fax: 91-22-26524982
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About Us

CBS was set up by the Department of Atomic Energy and the University of Mumbai in 2007. CBS offers a 5 year integrated MSc program in Basic Sciences, with undergraduate teaching embedded in a postgraduate and research environment, for students who have completed 10+2 schooling or its equivalent.